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Image Search Results
Journal: Acta Pharmaceutica Sinica. B
Article Title: Emerging vaccine nanotechnology: From defense against infection to sniping cancer
doi: 10.1016/j.apsb.2021.12.021
Figure Lengend Snippet: Schematic illustration of emerging vaccine nanotechnology for infectious diseases prevention and cancer immunotherapy. Main types of nanovaccines include self-assembled protein nanoparticles, inorganic nanoparticles, polymeric and liposomal nanoparticles and biomimetic nanoparticles.
Article Snippet: The successful clinical application of the
Techniques:
Journal: Acta Pharmaceutica Sinica. B
Article Title: Emerging vaccine nanotechnology: From defense against infection to sniping cancer
doi: 10.1016/j.apsb.2021.12.021
Figure Lengend Snippet: (A) Self-assembled protein nanoparticles as HIV vaccines. Fully assembled protein nanoparticles display 20 copies of trimers. The protein nanovaccine induces specific IgG in mice and the immune response can be enhanced with army liposome formulation (ALF) as adjuvant. Reprinted with permission from Ref. . Copyright © 2019. Elsevier. (B) Design and application of high-density lipoprotein-mimicking nanodisc platform composed of lipids and peptides for co-delivery of Ag and CpG for as cancer vaccine. Subcutaneous injection of the nanovaccine induce DC maturation and elite robust Ag-specific CD8 + T cell responses, killing target cancer cells. This nanovaccine can be used in combination immunotherapy with immune checkpoint blockade. Reprinted with permission from Ref. . Copyright © 2017 Springer Nature.
Article Snippet: The successful clinical application of the
Techniques: Injection
Journal: Acta Pharmaceutica Sinica. B
Article Title: Emerging vaccine nanotechnology: From defense against infection to sniping cancer
doi: 10.1016/j.apsb.2021.12.021
Figure Lengend Snippet: (A) Gold nanoparticle (GNP) decorated with high-mannoside-type oligosaccharides (P1@HM) and HIV-1-peptides-pulsed DC for HIV-specific T cell immunity. Reprinted with permission from Ref. © Copyright 2018. Elsevier. (B) Fabrication of PLGA nanoparticle loaded with tumor antigen, metformin and hollow gold nanospheres (TA-Met@MS) as tumor vaccines. Photothermal therapy (PTT) stimulate the nanoparticle to release antigen and drug for inducing immunogenicity. (C) TA-Met@MS treatment prolonged the survival of tumor bearing mice and suppressed tumor progression. Reprinted with permission from Ref. . Copyright © 2021 Elsevier.
Article Snippet: The successful clinical application of the
Techniques:
Journal: Acta Pharmaceutica Sinica. B
Article Title: Emerging vaccine nanotechnology: From defense against infection to sniping cancer
doi: 10.1016/j.apsb.2021.12.021
Figure Lengend Snippet: Typical clinical approved vaccines and candidates using nanotechnology for addressing infectious disease or cancer.
Article Snippet: The successful clinical application of the
Techniques: Recombinant